humoral immunity

definition : ( CD20 )
antibody mediated which is the function of B-cells , it is converted into plasma cells taht produce antibody IgA IgM IgG IgD IgE .
IgA : surface antibody attack bacteria on the body surface like GI lumen respiratory lumen
IgM : the largest and first one produced in responce to bacteria means acute infection .
IgG : the smallest , only that cross the placenta , remains in serum as memory for old infection .
IgE : responsible fpr allergy stimulate mast cells to release histamine .
IgD : least important

deficiency in humoral immunity increase risk of infection mainly bacteria ( encapsulated ) 

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